Cyclobenzaprine and tizanidine are two medications commonly prescribed to manage muscle spasms and associated discomfort. Both belong to the category of muscle relaxants but differ significantly in their mechanisms of action, indications, and side effects. Understanding these differences is crucial for healthcare providers and patients alike, as it can influence treatment choices and outcomes. Cyclobenzaprine is primarily used for short-term relief of muscle spasms, often resulting from acute musculoskeletal conditions. It works by acting on the central nervous system, helping to reduce muscle tightness and discomfort. On the other hand, tizanidine operates differently by acting as an alpha-2 adrenergic agonist, which decreases spasticity by inhibiting the release of excitatory neurotransmitters.…