The equine world is filled with various medications and treatments, each designed to address specific health issues in horses. One such treatment that has gained popularity among horse owners is phenylbutazone, commonly known as “bute.” This non-steroidal anti-inflammatory drug (NSAID) has been used for decades to manage pain and inflammation in horses. While its effectiveness is widely recognized, understanding the nuances of its use, benefits, and potential risks is crucial for anyone involved in equine care. Bute works by inhibiting cyclooxygenase enzymes, which play a key role in the production of prostaglandins—compounds that promote inflammation, pain, and fever. By reducing these inflammatory responses, bute provides relief to horses suffering from…