The use of medications in equine care has always been a topic of significant interest and debate among horse owners, trainers, and veterinarians. Among these medications, phenylbutazone, commonly known as Bute, has garnered attention for its effectiveness in managing pain and inflammation in horses. This non-steroidal anti-inflammatory drug (NSAID) has been a staple in equine medicine for decades, particularly in the context of treating musculoskeletal issues, which are prevalent in performance and racehorses. Despite its benefits, the use of Bute is not without controversy. Concerns about its long-term effects, potential side effects, and implications for horse welfare have sparked discussions within the equestrian community. As horse owners seek to ensure…